https://blog.csdn.net/weixin_42347486/article/details/116667172
https://zhuanlan.zhihu.com/p/517804965
~/.Rprofile
options("repos" = c(CRAN="https://mirrors.tuna.tsinghua.edu.cn/CRAN/"))
options(BioC_mirror="https://mirrors.tuna.tsinghua.edu.cn/bioconductor")
Sys.setlocale("LC_MESSAGES", "en_US.utf8")
https://support.rstudio.com/hc/en-us/articles/360047157094-Managing-R-with-Rprofile-Renviron-Rprofile-site-Renviron-site-rsession-conf-and-repos-conf